The Mac version of "Trend Micro Apex One" distributed by this center will be compatible with Big Sur (11.0) by the end of December 2020.

Support for macOS Big Sur (Trend Micro official)

"2020年12月中対応予定":Scheduled to be supported in December 2020

If you are using Apex One for Mac, please wait for a while to upgrade to mac OS 11 Big Sur.